Immune Recognition of HLA-E

Grant number: 509179 | Funding period: 2008 - 2010

Completed

Abstract

HLA-E, a protein expressed by all cells regulates both innate and adaptive immune responses by binding to receptors found on white blood cells. This project will examine different ways that lymphocytes recognise this protein and its role in infection and transplantation.

Related publications (1)

The presence of HLA-E-Restricted, CMV-Specific CD8 T Cells in the blood of lung transplant recipients correlates with chronic allograft rejection

LC Sullivan, GP Westall, JML Widjaja, NA Mifsud, THO Nguyen, AC Meehan, TC Kotsimbos, AG Brooks, P Chen

2015-08-24

The human cytomegalovirus (CMV) immune evasion protein, UL40, shares an identical peptide sequence with that found in the leader s..

University of Melbourne Researchers

Andrew Brooks